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Typhi and S. Spanish adventurers followed Columbus to the Bahamas and soon shipped the remaining Lucayan population as slaves to mines in Cuba and Santo Domingo, where the race was extinguished. B) between gal and bio operons; int, integrase for integration and with xis λ prophage excision; xis, excisionase for λ prophage excision; exo, 5 to 3 exonuclease for recombination; bet, promotes annealing of complementary ssDNA strands for recombination; gam, inhibits host RecBCD nuclease; kil, host killing by blocking cell division; cIII, required for establishment of lysogeny, CIII blocks degradation of CII by host proteases (HflA and HflB); ral (restriction alleviation), for partial alleviation of host B and K restriction systems; N, anti-terminator protein promotes expression of delayed early genes, causes RNA polymerase to overcome transcription terminators and not stop transcription, requires nut (N utilization) site and host factors; rex [rexBrexA] (restriction of exogenous phage), blocks superinfection by phage such as P22, expressed in the lysogen; cI, λ repressor binds to OL and OR to repress transcription from PL and PR, activates transcription from PRM when bound to OR2, cI expressed from PRE to establish lysogeny and from PRM to maintain lysogeny; cro, anti-repressor binds to OL and OR to repress early transcription, block activation of PRM and promote the lytic cycle; cII, regulatory protein for establishment of lysogeny, activates transcription from PRE for CI synthesis, PI for integrase synthesis, PaQ for antisense Q resulting in reduced expression of Q.
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